Thread group: For any test plan, JMeter is the beginning part of thread group elements. It is an important element of JMeter, where you can set a number of users and time to load all the users given in the thread group.
Samplers: Sampler generates one or more sample results; these sample results have many attributes like elapsed time, data size, etc. Samplers allow JMeter to send specific types of requests to the server, through samplers, thread group decides which type of request it needs to make. Some of the useful samplers are HTTP request, FTP request, JDBC request and so on.